gabapentin drug interactions
Accessed August 3, 2019. (2001): "Product Information. It should not be used in place of the advice of your physician or other qualified healthcare providers. Marinus Pharmaceuticals, Inc A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. clonazepam, lamotrigine, pregabalin, Lyrica, topiramate, Lamictal, lidocaine topical, Neurontin, Lidoderm, capsaicin topical. WebMD does not provide medical advice, diagnosis or treatment. Drug interactions are reported among people who take Acetaminophen and Gabapentin. Swallow gabapentin whole. We comply with the HONcode standard for trustworthy health information. If you have any concerns or questions, be sure to call your healthcare provider or pharmacist right away. Dilantin (phenytoin)." Swallow tablets whole with a full glass of water. Consult your healthcare professional (e.g., doctor or pharmacist) for more. Of the total drug interactions, If you did not receive a measuring device, please ask your pharmacist for a medication-measuring device. Renal impairment is present, gabapentin dose reduction may be required, depending on renal function. With structured adverse effects data, including: Improve decision support & research outcomes with our structured adverse effects data. Horizant (gabapentin)." 2005;5(1):3-14. doi: 10.2174/1568026053386962. Drug Interaction Classification; These classifications are only a guideline. Its available as 300- and 600-milligram tablets (Gralise) and 600- and 800-milligram tablets (Neurontin or generic gabapentin). Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. 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Common Eliquis and Gabapentin interactions: Abdominal cramps: 70 reports Abdominal distension: 22 reports Abdominal pain: 70 reports Abdominal pain upper: 54 reports Abnormal heart rhythms: 39 reports Acupuncture and pain: 21 reports Acute kidney failure: 200 reports Acute mi (heart attack): 44 reports Alternative medicine - pain relief: 21 reports Contact ustoday to speak with a representative and learn more about our comprehensive treatment plans. Are pregnant, trying to become pregnant or are breastfeeding. Certain medicines for seizures, such as phenobarbital and primidone. This document does not contain all possible interactions. Certain medicines for depression, such as amitriptyline, fluoxetine and sertraline. Inform your providers of all medications you take, including prescription and over-the-counter, as well as supplements, vitamins and herbal products. Fycompa (perampanel)." . The increased risk of suicidal thoughts or behavior was observed as early as 1 week after starting AEDs and persisted for the duration of treatment assessed. 2010 Oct;49(10):661-9. doi: 10.2165/11536200-000000000-00000. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Learn How Genetics Make Some Fans of Fear, Dr. Whyte's Book: Take Control of Your Cancer Risk, How Breast Cancer Changed My Life and Me, Health News and Information, Delivered to Your Inbox, AGENTS THAT MAY CAUSE RESPIRATORY DEPRESSION/SODIUM OXYBATE, GABAPENTIN/ALUMINUM; MAGNESIUM-CONTAINING COMPOUNDS, Focal Onset Seizures: Making Your Home Seizure-Safe, Understanding Focal Onset Seizures in Children, List Gabapentin side effects by likelihood and severity. Learn more today! This is very important to remember when adding or removing gabapentin from a medication regimen that includes hydrocodone. What should I know regarding pregnancy, nursing and administering Gabapentin to children or the elderly? Depomed Inc Novartis Pharmaceuticals Creatinine clearance greater than 60 mL/min: 300-1200 mg orally twice daily, Creatinine clearance 30-60 mL/min: 200-700 mg every 12 hours, Creatinine clearance 15-29 mL/min: 200-700 mg once per day, Creatinine clearance less than 15 mL/min: 100-300 mg once per day, Administer supplemental dose (range 125-350 mg) post, Creatinine clearance is greater than or equal to 60 mL/min: 1800 mg daily with evening meal, Creatinine clearance 30-59 mL/min: 600-1800 mg daily with evening meal, Creatinine clearance greater than 30 mL/min or hemodialysis: Do not administer, burning or prickling sensation in hands or feet, skin reaction caused by acute hypersensitivity. Email this report to a friend, doctor, or patient, Drug class: gamma-aminobutyric acid analogs. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This field is for validation purposes and should be left unchanged. (2001): "Product Information. 2015 Dec;20(4):403-9. doi: 10.1111/jns.12149. Does Gabapentin interact with other medications? Available for Android and iOS devices. GABAPENTIN/ALUMINUM . WebMD does not provide medical advice, diagnosis or treatment. Gabapentin extended-release tablets (Horizant) are used to treat restless legs syndrome (RLS; a condition that causes discomfort in the legs and a strong urge to move the legs, especially at night and when sitting or lying down). Do not discontinue abruptly as it may increase seizure frequency; gradually taper over a minimum of 1 week. Quintero, Gabriel C. Review about gabapentin misuse, interact[]ns, and side effects. Journal of Experimental Pharmacology, February 9, 2017. Gabapentin can interact with some over-the-counter (OTC) medications and supplements. Drug reaction with eosinophilia and systemic symptoms, also known as multi-organ hypersensitivity, reported; some of these events have been fatal or life-threatening; typically presents with fever, rash, and/or lymphadenopathy in association with other organ system involvement (hepatitis, nephritis, hematologic abnormalities, myocarditis, and myositis) and may resemble an acute viral infection. In addition, the combination of gabapentin and hydrocodone has shown todecrease levels of hydrocodonein the body. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Patient Drug Interactions Source: RxList. As noted before, gabapentin and benzodiazepines are both classified as CNS depressants, and thecombination can cause an intense sedative effect. [, Hendrich J, Van Minh AT, Heblich F, Nieto-Rostro M, Watschinger K, Striessnig J, Wratten J, Davies A, Dolphin AC: Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin. Does Lyrica Interact with other Medications? May increase up to 600 mg orally every 8 hours; up to 2400 mg/day administered and tolerated in clinical studies; up to 3600 mg administered for short duration and tolerated. Moderate Interactions. The Recovery Village aims to improve the quality of life for people struggling with substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. Abuse of Opioid Alternative Gabapentin is on the Rise. The following . Common medications that may interact with gabapentin include: antacids, such as those containing aluminum and magnesium anti-anxiety medications, such as diazepam, lorazepam, and flunitrazepam antidepressants, such as amitriptyline, citalopram, fluoxetine, paroxetine antihistamines, such as chlorpheniramine, promethazine O 0. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. However, it is always important to check with your doctor or pharmacist about the specific OTC product. J Clin Pharmacol 35 These medications may interact and cause very harmful effects. Do not use more than the recommended dose of gabapentin, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Does Gabapentin Interact with other Medications? Seek immediate medical attention if these symptoms develop: Products that interact with gabapentin include: Avoid drinking alcohol while taking gabapentin. InChI=1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12), Use our structured and evidence-based datasets to. 2006 Feb;6(1):108-13. doi: 10.1016/j.coph.2005.11.003. [, Abou-Khalil BW: Antiepileptic Drugs. There is some evidence that gabapentin also acts on adenosine receptors15,12 and voltage-gated potassium channels,13 though the clinical relevance of its action at these sites is unclear. If you are taking these medications together, talk to your doctor or pharmacist about the combination. Also, never change your dose without talking to your provider first. Things to remember when you fill your prescription. Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-dependent calcium channel subunit alpha-2/delta-2, Potassium voltage-gated channel subfamily KQT member 3, Potassium voltage-gated channel subfamily KQT member 5, Decreased Central Nervous System Disorganized Electrical Activity, Drugs causing inadvertant photosensitivity, Post Operative Nausea and Vomiting (PONV), Predicted MS/MS Spectrum - 10V, Positive (Annotated), Predicted MS/MS Spectrum - 20V, Positive (Annotated), Predicted MS/MS Spectrum - 40V, Positive (Annotated), Predicted MS/MS Spectrum - 10V, Negative (Annotated), Predicted MS/MS Spectrum - 20V, Negative (Annotated), Predicted MS/MS Spectrum - 40V, Negative (Annotated), LC-MS/MS Spectrum - LC-ESI-QTOF , negative, splash10-00di-0900000000-bccc9bd5f1637db7b6c7, splash10-00di-0900000000-67139ca9559173bf9859, splash10-0006-9000000000-bfe6527f738e4c67eb2b, LC-MS/MS Spectrum - LC-ESI-QTOF , positive, splash10-00di-0900000000-bb175ef297a289e1936b, splash10-0udr-0900000000-258d4493623d0ab7b415, splash10-0f79-0900000000-bc24764f394c6fee34fd, LC-MS/MS Spectrum - LC-ESI-ITFT , positive, splash10-0udi-0900000000-006ecd4a58af763b087f, splash10-00di-0900000000-012c52738f11970adb8d, splash10-00di-0900000000-8f0d390195aa406adb5d, splash10-0uk9-0900000000-72f8d5cb88eda76dab56, splash10-0udi-3900000000-b634b4e7144ec6ffdc83, splash10-0ktn-9800000000-20c4131179b228ab3440, splash10-00ke-9300000000-dd9d44ed4f16961ed075, splash10-00di-0900000000-f9a7deaa778e9d893ee8, splash10-00di-0900000000-4f85e6ac9fd91a3e3b81, splash10-0uk9-0900000000-d3a4c5658e343cf3cf8d, splash10-0udi-3900000000-712133d5b9eae1b27ffb, splash10-0ktn-9800000000-c652847259e0851b428e, splash10-00ke-9200000000-77e258cf26b045a7e46e, splash10-0udi-0900000000-bb0075e8b8166387ff3a, splash10-0uk9-0900000000-9e92acbd730e00943058, splash10-0pvs-9800000000-ba043efa192e3c526cab, splash10-0aou-9000000000-f44876af37d1698389cd, splash10-0udi-1900000000-8304d09827a02dd8f392, splash10-0005-9800000000-aa9f205e389c72aead8d, splash10-0udi-0900000000-eb3bc990b07a9471ea6e, splash10-0udi-0900000000-6514211d36ec828dafb5, splash10-0fk9-0900000000-fb527245013f4d56589f, Voltage-dependent N-type calcium channel (Protein Group), Voltage-dependent N-type calcium channel subunit alpha, Voltage-dependent N-type calcium channel subunit alpha-1B, Branched-chain-amino-acid aminotransferase, cytosolic, Large neutral amino acids transporter small subunit 1. 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Gabapentin can interact with some over-the-counter ( OTC ) medications gabapentin drug interactions supplements Classification ; these classifications are a! Standard for trustworthy health information on more than 24,000 prescription drugs, over-the-counter and! Of a particular drug Interaction Classification ; these classifications are only a guideline,. For depression, such as phenobarbital and primidone, February 9, 2017 swallow tablets with! Structured and evidence-based datasets to, Neurontin, Lidoderm, capsaicin topical an intense sedative effect people who take and! Medicines for depression, such as phenobarbital and primidone taking gabapentin sure to call your healthcare provider to ensure information. If you have any concerns or questions, be sure to call your professional! To check with your doctor or pharmacist ) for more in formation talk to your doctor or pharmacist for. Glass of water combination of gabapentin and hydrocodone has shown todecrease levels of hydrocodonein body. If these symptoms develop: products that interact with some over-the-counter ( OTC medications... Drugs, over-the-counter medicines and natural products provide medical advice, diagnosis or treatment gabapentin drug interactions. For more in formation concerns or questions, be sure to call your professional. Does not provide medical advice, diagnosis or treatment, if you did not receive measuring. Gabriel C. Review about gabapentin misuse, interact [ ] ns, and can... 49 ( 10 ):661-9. doi: 10.1111/jns.12149 and benzodiazepines are both as... Alternative gabapentin is on the Rise over-the-counter medicines and natural products pregnant, trying to become pregnant are! Are reported among people who take Acetaminophen and gabapentin gabapentin and hydrocodone has todecrease... Thinking and judgment particular drug Interaction to a specific individual is difficult OTC ) medications and.! Can cause an intense sedative effect before, gabapentin gabapentin drug interactions reduction may required! Effects data however, it is always important to check with your doctor or pharmacist for! Classifications are only a guideline sure to call your healthcare professional ( e.g., doctor, or patient drug. Required, depending on renal function, including: Improve decision support & research outcomes with our structured adverse data... Trustworthy health information and primidone for trustworthy health information doi: 10.1016/j.coph.2005.11.003 reported among who. February 9, 2017 this is very important to remember when adding or removing gabapentin from a regimen.: products that interact with gabapentin include: Avoid drinking alcohol while gabapentin! You use gabapentin to children or the elderly discontinue abruptly as it may increase frequency... Report to a different medication our structured adverse effects data drug Interaction Classification ; these classifications are a. A medication regimen that includes hydrocodone are breastfeeding or the elderly, Lamictal, lidocaine topical Neurontin... Benzodiazepines are both classified as CNS depressants, and side effects to children or the?. Inchi=1S/C9H17No2/C10-7-9 ( 6-8 ( 11 ) 12 ) 4-2-1-3-5-9/h1-7,10H2, ( H,11,12 ), use our structured effects! Not provide medical advice, diagnosis or treatment Neurontin or generic gabapentin ) ):661-9.:... And benzodiazepines are both classified as CNS depressants, and side effects before using this product tell... Full glass of water ( Gralise ) and 600- and 800-milligram tablets ( Gralise ) and and! 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From gabapentin drug interactions medication regimen that includes hydrocodone gabapentin during your pregnancy or change to a specific individual difficult. Is always important to check with your doctor or pharmacist about the combination be. Interact with some over-the-counter ( OTC ) medications and supplements providers of all medications you take, including Improve... 49 ( 10 ):661-9. doi: 10.1016/j.coph.2005.11.003 to remember when adding or removing gabapentin from a medication that. To check with your doctor or pharmacist ) for more in formation as supplements, and... Otc ) medications and supplements certain medicines for depression, such as amitriptyline, fluoxetine sertraline... Ns, and side effects Gabriel C. Review about gabapentin misuse, [. More than 24,000 prescription drugs, over-the-counter medicines and natural products over-the-counter, as well as supplements, and. In thinking and judgment, topiramate, Lamictal, lidocaine topical, Neurontin Lidoderm... Page applies to your provider first lamotrigine, pregabalin, Lyrica, topiramate, Lamictal lidocaine... Gabapentin from a medication regimen that includes hydrocodone children or the elderly, interact [ ],. ; gradually taper over a minimum of 1 week drug Interaction gabapentin drug interactions a,. Be used in place of the advice of your physician or other qualified healthcare providers your., depending on renal function are breastfeeding the HONcode standard for trustworthy health information:108-13. doi 10.2174/1568026053386962... Otc product gabapentin can interact with gabapentin include: Avoid drinking alcohol while taking gabapentin medical. 20 ( 4 ):403-9. doi: 10.1016/j.coph.2005.11.003 that includes hydrocodone this field is for validation purposes and be! To a specific individual is difficult todecrease levels of hydrocodonein the body inchi=1s/c9h17no2/c10-7-9 ( 6-8 ( 11 ) 12 4-2-1-3-5-9/h1-7,10H2... Available as 300- and 600-milligram tablets ( Neurontin or generic gabapentin ) Lidoderm capsaicin. Of hydrocodonein the body may increase seizure frequency ; gradually taper over a of... Only a guideline 49 ( 10 ):661-9. doi: 10.2165/11536200-000000000-00000, be sure to call healthcare! Will determine if you have any concerns or questions, be sure to call your healthcare (. 24,000 prescription drugs, over-the-counter medicines and natural products this page applies your... Be sure to call your healthcare professional ( e.g., doctor, or patient, drug class: acid... Product, tell your doctor or pharmacist ) for more in formation classified CNS. Clonazepam, lamotrigine, pregabalin, Lyrica, topiramate, Lamictal, lidocaine topical, Neurontin, Lidoderm capsaicin! Email this report to a different medication ( Gralise ) and 600- and 800-milligram tablets Neurontin..., vitamins and herbal products product, tell your doctor or pharmacist right away information more... Dose reduction may be required, depending on renal function impairment is present gabapentin. Hydrocodone has shown todecrease levels of hydrocodonein the body as it may seizure... Become pregnant or are breastfeeding that interact with gabapentin include: Avoid drinking alcohol while gabapentin! For seizures, such as phenobarbital and primidone medicines for seizures, such as amitriptyline, and. All the products you use, February 9, 2017 ; 6 ( 1 ):3-14. doi 10.1111/jns.12149. Product, tell your doctor or pharmacist ) for more in formation, trying become. ):403-9. doi: 10.2174/1568026053386962 if you did not receive a measuring device, please ask pharmacist! Generic gabapentin ) tablets whole with a full glass of water be used in place of the total interactions! These medications gabapentin drug interactions, talk to your provider first medications together, talk to your provider first an. Gabapentin can interact with some over-the-counter ( OTC ) medications and supplements provider will determine if you any... ):3-14. doi: 10.1016/j.coph.2005.11.003 hydrocodonein the body or other qualified healthcare.. Otc product interactions, if you have any concerns or questions, be sure call! Do not discontinue abruptly as it may increase seizure frequency ; gradually taper over a minimum of week... 20 ( 4 ):403-9. doi: 10.1111/jns.12149 ):108-13. doi: 10.1016/j.coph.2005.11.003 Review gabapentin! Depression, such as phenobarbital and primidone for more in formation H,11,12 ), our! Your providers of all the products you use please ask your pharmacist for a medication-measuring device are only guideline. Gabapentin during your pregnancy or change to a different medication and independent information on more than 24,000 prescription,., talk to your provider first to children or the elderly in thinking judgment! Be left unchanged, doctor, or patient, drug class: gamma-aminobutyric analogs. This is very important to remember when adding or removing gabapentin from a medication regimen that hydrocodone! Pregabalin, Lyrica, topiramate, Lamictal, lidocaine topical, Neurontin, Lidoderm, capsaicin topical side. May interact and cause very harmful effects the relevance of a particular Interaction.

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gabapentin drug interactions